Comprehensive
Canine DNA Screen
Advanced Genomics Testing for your Dog’s Health
Profile. Diagnose. Manage.
Use genomic testing to profile, identify, diagnose, manage, and prevent genetic disorders in dogs
Harness rapid advances in genomics
For diagnosis, management and prevention of genetic diseases in canines
Around 400 hereditary diseases known in canines are caused by mutations in 19,000 genes spread across 78 chromosomes. Until now, lab tests are ordered only after symptoms are observed, for a given suspected disease. This leaves little scope for prevention or management as the disease is already set in. Today, genomics allows us to identify hundreds of diseases in advance, at a time, in a single lab test. This makes it possible to profile the pets in advance, take preventive measures, and provide better care for the pet.
How does Genetic Testing help you?
> Accurate diagnosis
Identify most commonly prevalent genetic diseases associated with the pet and understand future risks
> Disease management
Profiling for diseases in advance gives more time for management of diseases before they set in
> Trait information
Genetic markers help you identify traits of the breed such as coat color, type, hair length and tail
> Personalized Pet Care
Design your pet diet, environment and care based on specific risks identified in the test
> Better breeding
Identifies carrier status for diseases, allows choice of right parents to reduce disease risk in pups
Canine Genomics at GeneTech
> Canine DNA Screen – what does it offer?
GeneTech’s Canine DNA Screen genetic panel is based on Thermofisher’s Canine Disorders and Traits Panel which was developed based on extensive research in Canine Genomics and Veterinary Science. It offers screening for all diseases recommended by ISAG (International Society for Animal Genetics) and more.
The panel identifies gene variants that are associated with 136 common inherited conditions in different dog breeds. It also provides information on 18 different breed traits like coat color, coat type, hair type, hair length, tail length, and so on.
Disease and trait information is crucial for modern dog breeding programs. As carrier status is also reported, breeders can use the test to choose the right parents without any carrier risks for breeding.
> What is the turn around time for the report?
The report will be delivered in 2-3 weeks
> What sample should be sent for testing?
2ml blood in EDTA vacutainer – OR – Swab collected using GeneTech supplied swab kit.
List of disorders tested in the Canine DNA Screen genomic panel
Achromatopsia (cone degeneration)
Hemeralopia, AMAL & GSPT
Achromatopsia-2
Alopecia, colour mutant
Amelogenesis imperfecta
Ataxia, cerebellar, ATP1B2-related
Ataxia, cerebellar, KCNJ10-related
Ataxia, cerebellar, progressive
early-onset
Ataxia, spinocerebellar
CAPN1-related
Bleeding disorder
Due to P2RY12 defect
Brachycephaly
C3 deficiency
Cerebellar abiotrophy
Cerebellar cortical degeneration
Hungarian Vizsla
Cerebellar hypoplasia
VLDLR-associated
Chondrodysplasia
Disproportionate short-limbed
Ciliary dyskinesia, primary
Cone-rod dystrophy Type 1, 2 & 3
Craniomandibular osteopathy
Cystinuria, type I – A, type II – A & B
Degenerative myelopathy
Dental hypomineralization
Dwarfism, pituitary
Ectodermal dysplasia
Epilepsy, benign familial juvenile
Factor VII deficiency
Gallbladder mucoceles
Gangliosidosis, G M1
Gangliosidosis, GM1 (Alaskan Husky)
Gangliosidosis, GM1-PWD, GM2- II
Glaucoma
Glaucoma, primary open angle
ADAMTS10-related
Glycogen storage dis Ia, II, IIIa & VII
Golden Retriever PRA 2
Haemophilia B
Hyperkeratosis, epidermolytic
Hyperkeratosis, palmoplantar
Hypocatalasia
Hypomyelination
Of the central nervous system
Hypothyroidism
Ichthyosis, ASPRV1-related
Ichthyosis, Golden Retriever
TGM1-related
Ichthyosis, SLC27A4-related
Intestinal cobalamin malabsorption
CUBN-related
Krabbe disease
L-2-hydroxyglutaricacidemia
Leber congenital amaurosis
(congenital stationary night blindness)
Lens luxation
Leukocyte adhesion deficiency I & III
Macular corneal dystrophy
Menkes disease
Mucopolysaccharidosis IIIa & VII
Multifocal retinopathy 1, 2 & 3
Muscular dystrophy, Duchenne type
Muscular hypertrophy
(double muscling)
Musladin-Lueke syndrome
Myasthenic syndrome, congenital
Myopathy, Great Dane
Myotonia
Myotubular myopathy 1
Narcolepsy
Neonatal encephalopathy
With seizures
Nephritis, X-linked
Neuroaxonal dystrophy
Neuronal ceroid lipofuscinosis
Types 1, 10, 12, 4A, 5, 6 and 8
Osteogenesis Imperfecta
Osteogenesis imperfecta, type III
COL1A1-related
Osteogenesis imperfecta Dachshund
SERPINH1-related
Persistent Mullerian duct syndrome
Polycystic kidney disease
Polycythemia
Polyneuropathy
Polyneuropathy, ARHGEF10-related
Polyneuropathy, NDRG1-related
Polyneuropathy, RAB3GAP1-related
Prekallikrein deficiency
Progressive retinal atrophy
Progressive retinal atrophy, Basenji
Progressive retinal atrophy CNGA1-related
Pyruvate dehydrogenase deficiency
Pyruvate kinase deficiency
Of erythrocyte
Renal cystadenocarcinoma
Nodular dermatofibrosis
Rod-cone dysplasia – Types 1, 1a & 3
Scott Syndrome
Severe combined immunodeficiency
Autosomal & X-linked
Severe combined immunodeficiency
T cell -ve, B cell -ve, NK cell +ve
Skeletal dysplasia 2 (Sd2)
Thrombasthenia
Thrombocytopaenia
Thrombopathia
Trapped Neutrophil Syndrome
Tremor, X-linked
Urolithiasis
Vitamin D-deficiency rickets, type II
Von Willebrand disease
Types I, II and III
Wilson disease
